The liquids in an enema help in lubricating and softening the stool so that there is no strain while emptying the bowels. These liquids are usually water or saline based and can also use Epsom salt, Sodium Phosphate, Lemon juice, Apple Cider Vinegar, Soap suds etc. Enema has been used from hundreds of years and is proven to be safe. It can be administered at a hospital by a professional or you can administer it yourself at home.